High doses used to treat rejection may cause euphoria an extreme feeling of well-being that wears off in a few days. Be aware that these feelings are usually temporary. Insomnia difficulty sleeping. This effect occurs more often with higher doses. Osteoporosis weakening of bones. This side effect occurs after long-term use of prednisone. It is important for your child to get the necessary calcium every day, either through diet or through a supplement. This is especially important for girls. Blood calcium levels do not indicate whether your bones are receiving sufficient calcium — your body will take calcium from your bones to maintain a normal calcium level in the blood.
Cataracts or glaucoma. Prednisone may cause blurry vision or a change in eyesight. More serious conditions, such as glaucoma and cataracts, can occur after long-term prednisone use. If your child has a history of vision problems, alert your coordinator to see if your dosage of prednisone can be reduced or eliminated.
Steroid dependency. The human body makes a hormone that is very similar to prednisone. To maintain a balance, the body may stop making this hormone while on prednisone. This is one reason why prednisone usage should not be stopped suddenly; rather, the dosage should be reduced gradually.
Sudden withdrawal can cause extreme fatigue, weakness, stomach upset, or dizziness; it also can be life threatening. Notify your primary care doctor that your child is taking, or was taking, steroids. Because prednisone inhibits the immune system, it decreases the ability to fight infection. Any infections your child does pick up may show fewer symptoms.
Slowed wound healing. Bruising, rashes, and other skin changes. Because taking prednisone can make your child more vulnerable to sunburn, and because those who are immunosuppressed have a greater risk of getting skin cancer, avoid excessive sunlight. If your child plays in the sun, make sure to use a sunscreen with a sun protection factor SPF of at least Hats provide additional protection.
Rare side effects include: Blood in urine, stools, or vomit Severe nausea or vomiting Headache Muscle weakness Prolonged sore throat Fever Difficult breathing Prednisone Drug Interactions Tell your transplant doctor or pharmacist about any prescription or over-the-counter medication your child is taking, so that you can be warned of interactions and prevent them.
Prednisone Storage Store prednisone at room temperature. Precautions for Children and Teens Take prednisone exactly as prescribed. The dose of this medicine will be different for different patients.
Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. There is a problem with information submitted for this request. Sign up for free, and stay up-to-date on research advancements, health tips and current health topics, like COVID, plus expert advice on managing your health.
Error Email field is required. It does not follow the concept that hormones must follow the circadian rhythm of endogenous production. In healthy patients, nighttime inflammation makes sense.
The inflammatory system takes advantage of calories unavailable when muscles are in motion and digestion is active to attack pathogens or heal injuries. The system follows a clock set by the suprachiasmatic nucleus, which responds to light and dark and sets the pace for such functions as sleep, heart rate, blood pressure and body temperature. Acting on the endocrine system, it increases the production of melatonin and prolactin around 9 p.
Cutolo says. Then around 3 a. In people with rheumatoid arthritis, this system is dysregulated, he explains. In particular, cortisol becomes less available in the wee hours of the morning.
As a result, inflammation lingers as patients rise. Exogenous glucocorticoids such as prednisone can take the place of the missing cortisol.
Although prednisone plays a smaller role in the treatment of rheumatoid arthritis since the advent of drugs with fewer side effects, it can still be useful in low doses, Dr.
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